Air Arabia Maroc will begin twice-weekly flights from Manchester to Agadir from October.
The move makes Manchester the only airport in the UK outside of London served by the low-cost carrier.
The new service will operate Thursdays and Sundays on an Airbus A320, with fares from £60 one way.
Adel Al Ali, group chief executive officer of Air Arabia, said: “We are confident that this step will further cater to the needs of our growing customer base. Agadir offers a great tourism experience year around with its unique beaches, mountains, golf resorts and excellent dining options”.
Stephen Turner, commercial director for Manchester Airport, added: “Agadir is a great beach resort that also offers fantastic access to the Atlas Mountains. This route will provide the 22million people in our catchment area with further choice on how to reach this exciting destination.”