DFDS is restoring its Newcastle-Amsterdam sailings from July 16.
The route has been suspended since the UK lockdown in March.
Passenger capacity will be reduced to maximise the space available on board and ensure that travellers can comply with government guidance.
Early and staggered boarding and disembarkation procedures will be in place, crew will wear protective equipment and passengers are advised to wear face coverings for embarkation and disembarkation.
The ferry company is now taking bookings for the summer and beyond after the Netherlands was included in countries where UK quarantine restrictions will be removed.
DFDS routes across the English Channel from Dover to Dunkirk and Calais, and its Newhaven to Dieppe services will be open for holidaymakers from July 10.
The company continued to operate these services during lockdown to carry freight bringing vital goods into the UK and to enable essential travel for passengers.
Travellers booking crossings on the Dover routes receive a free meal on board during their sailing.
Kasper Moos, head of short routes and passenger for DFDS, said: “We welcome the government’s announcement that travel restrictions will be removed and that holidaymakers will be able to explore continental destinations this summer.
“Our teams have been working hard to prepare our ships to restart sailings and we’re really looking forward to welcoming passengers back on board our services next week.”