A new Manchester to Seattle service is to be introduced as part of Thomas Cook Airlines’ summer 2018 long-haul programme.
Flights will run twice a week from May 27 using one of eight Airbus A330s based at Manchester airport.
Return fares start at £399.
The new transatlantic destination follows the introduction of San Francisco and a year-round service to New York from Manchester.
Thomas Cook Group airline chief executive, Christoph Debus, said: “We are proud to be continuing our expansion to the USA by launching Seattle as a new destination next year.
“Our German Condor operation has served Seattle for many years and the year-round service has been really popular with our passengers.
“We work closely with partner airlines, allowing us to connect customers to 90 destinations within the USA. Alaska Airlines, based in Seattle, is an important partner offering our customers even more choice to the likes of British Columbia, Alberta, Alaska and Hawaii.”
Manchester airport interim managing director Collette Roche added: “To secure a direct route to Seattle is further testament to the role Manchester airport plays in the north and UK as a whole.
“We now offer more than a dozen direct destinations to the USA, meaning we have grown the number of seats on sale to US destinations at a greater rate than any other UK airport this year.
“This is hugely positive news for the 22 million passengers in our catchment area – which spans from Scotland to the Midlands and Merseyside to Yorkshire, and the millions of people a year who connect to our long haul network from locations across the UK and Europe.”