Stansted and Dublin will gain extra flights to Berlin and a new route will be opened to Glasgow as Ryanair opens a new base in the German capital.
The low-cost carrier is to add 16 routes to give a total of 22 from Berlin from October 27.
Five aircraft will be based in the German city as the airline adds routes to Alicante, Athens, Barcelona, Bari, Bologna, Bratislava, Brussels, Glasgow, Madrid, Malaga, Palermo, Palma, Riga, Rome, Venice and Valencia.
Frequency will rise to four flights a day to Stansted and nine a week to Dublin.
The expansion is expected to result in annual Ryanair carryings from Berlin rising to 2.6 million.
Chief marketing officer Kenny Jacobs said: “Germany is a significant growth market for Ryanair and as we announce our sixth German base at Berlin, we will continue to connect key German cities with Europe’s major centres of business.”