At least five people were killed and 65 injured when an Amtrak train derailed north of Philadelphia.
All six carriages and the engine came off the tracks in the incident.
The train was carrying 238 passengers and five crew from Washington DC to New York City when it derailed last night.
Philadelphia mayor Michael Nutter told the Associated Press that the train cars were “completely overturned, on their side, ripped apart”.
Amtrak said: “Initial reports are that several passengers have been injured and taken to local medical facilities for treatment.
“Local emergency responders are on the scene and an investigation is ongoing. Northeast Corridor service between New York and Philadelphia is suspended.”