Six Egyptian police officers are reported to have been killed in a bomb blast on a road used to transport tourists to the pyramids.

The explosion rocked a checkpoint near a mosque in the western Talibiya neighbourhood of the Egyptian capital Cairo shortly before Muslim Friday prayers this morning.

All of the victims were police officers either in or near their car while four civilians were hurt when the device went off near a bin.

The bomb went off on Pyramids road, the main avenue leading from the city centre out to the Giza pyramids, Mail Online reported.

The attack, close to a government building in a middle class neighbourhood of Cairo, was the latest in a series of security incidents in Egypt often claimed by radical Islamists.

Security forces killed three gunmen on Tuesday in a raid on a hideout in southern Egypt used by what they described as an armed wing of the Muslim Brotherhood, which claimed responsibility in September for an assassination attempt on a senior prosecutor.