Virgin Atlantic is returning to Cape Town with daily flights from Heathrow.
The service, suspended during the pandemic, resumes on November 5.
A three-class Boeing 787-9 will be deployed on the route with fares starting at £711 economy return.
The winter service runs until March 24, 2023, and will complement existing year-round daily flights to Johannesburg.
Chief commercial officer Juha Jarvinen said: “We’re incredibly excited to return to the fabulous city of Cape Town with daily services from November.
“Although a little later than we we’d have liked due to the Covid-19 pandemic, the move reflects the fact that travel is recovering and global demand for holidays to sunny, premium destinations is returning at pace.”
He added: “We’re expecting a high proportion of leisure travellers on this route who will rightly be taking advantage of the winter sun, exploring the world-renowned wine regions and soaking up the rich culture this incredible country has to offer.”