Around 70% of central Venice is under water due to flooding and strong winds.
Authorities said sea levels in the city reached a peak of five feet above normal due to heavy rain before receding slightly.
This brought the lagoon city’s high tide mark to its sixth-highest level since records began 150 years ago.
Around 200 people were evacuated from their homes in Tuscany due to heavy rain which flooded homes and caused mudslides.
The most affected region was the province of Massa and Carrara, where around 50 people were evacuated and a car was swept away by an overflowing river.
Italian authorities issued warnings and planned security measures to avoid casualties after 13 people died in Tuscany and Liguria a year ago, Sky News reports this morning.
The bad weather is said to be heading slowly towards the centre of the country and is set to hit Rome where civil defence forces have been put on alert.