Seven new routes are being introduced by British Airways from Manchester airport this summer.
Three additional routes are also being added from Stansted.
The airline will run summer-only flights from May to Alicante, Malaga, Ibiza, Palma, Mykonos, Nice and a link to London City airport from Manchester.
New flights from Stansted, part of the Manchester Airport Group, will serve Florence, Geneva and Nice.
There will also be increased frequency on existing routes to Ibiza and Palma while flights to Malaga and Faro will resume for the summer.
Embraer 190 jets will be deployed on all services.
Single fares from Manchester to Alicante, Ibiza, Nice and Palma start at £49, to Malaga from £59 and to Mykonos from £69.
The new flights from Manchester will operate weekly at weekends, with the exception of the Ibiza route which will operate three times a week, and will provide more than 35,000 extra seats from the north-west.
BA currently operates up to 10 return flights a day between Manchester and Heathrow.
The airline’s CEO and chairman Alex Cruz said: “We are very excited to be launching all these new routes from Manchester and Stansted, providing customers with flights to the sun direct from their doorstep with British Airways.
“These are the destinations that our customers tell us they want to fly to so we look forward to a busy summer.
“In addition, the Thursday night flight from London City, in the heart of the capital’s commercial district, will provide commuters with a valuable air link back to Manchester, with the return flight to London City on a Sunday.”