Loganair is returning to Teesside airport early next year with a network of five routes.
Flights to Aberdeen and Belfast City will operate from early February, with Dublin, Jersey and Newquay to be served from the summer.
The new partnership will see the Glasgow-based airline return to Teesside after quitting the airport in 2018.
Loganair will run up to seven flights a week to Dublin and Belfast City, six flights a week to Aberdeen, three a week to Cornwall Airport Newquay and twice weekly to Jersey.
Fares start at £49.99 one-way to Belfast City, £59.99 to Newquay and Dublin and £74.99 to Aberdeen and Jersey includng 15kg hold luggage plus 6kg hand luggage.
Loganair chief executive Jonathan Hinkles said: “We’re very happy to be returning to Teesside International. And we are back for good. We’re really looking forward to working with the team at the airport and the wider Tees Valley Combined Authority.
“There’s no doubt that air travel is having a difficult time right now, but I’m confident that our plans for Teesside International are both viable and appropriate now and for the longer term.”
Tees Valley mayor Ben Houchen added: “Even in these tough times, it’s fantastic to be welcoming yet another airline partner back to Teesside International, giving people from the region, the wider north-east and Yorkshire even more options when flying domestically from their local airport.
“As well as offering more flexibility for our passengers, Loganair is also reintroducing the much-loved summer route to Jersey. This is yet another great destination as we continue to expand our 2021 holidays schedule and give people something to look forward to in these difficult times.
“I’m looking forward to us working more closely together in the future to offer even more exciting destinations.”
Amanda Burns, chief executive of Visit Jersey, said: “We are thrilled to welcome visitors from the north east of England via this resumed Teesside route, which significantly improves connectivity to our island.
“We know that travel is a challenge at the moment, but with the return of this short-haul route comes the perfect opportunity for UK travellers to enjoy an idyllic domestic holiday. This is an excellent indicator that our island continues to be a desirable travel destination and we look forward to welcoming back visitors, both old and new, in 2021.”