Leeds/Bradford airport has been named as Monarch Airlines’ sixth UK base.
Up to 200 jobs could be created as the airline plans to start 12 new routes from the Yorkshire airport next year.
New services from next March will include scheduled flights to Barcelona, Rome, Larnaca and Tenerife.
Monarch managing director Kevin George said: “We will fly to places like Rome, Barcelona and Munich so there is potential for business travellers going out and business people coming out of Europe to West Yorkshire.
“It will strengthen our operations in the north of England. We estimate it will create about 200 jobs.”
The new roles include pilots, baggage staff and airport personnel, with recruitment due to begin in 2013.