Norwegian Cruise Lines will sail to and from Southampton in 2015 on Norwegian Epic.
It will be the first time that the ship has visited the port since its inaugural in June 2010.
The ship will sail on a six and seven-night Iberian Peninsula itinerary. The first will depart Barcelona on September 20 and arrive in Southampton on September 26, calling in Cartagena and Granada, Spain; and Lisbon, Portugal.
Following a 15-night dry dock in France, Norwegian Epic will than sail from Southampton to Barcelona on October 11 calling in Vigo, Spain; Lisbon, Portugal; Granada and Cartagena, Spain.
The ship will be based in Barcelona year-round in April 2015.
Prices start from £469 for the six-night cruise and £499 for the seven night sailing. Both cruises will be on sale from May 1.