No-frills carrier Norwegian has started serving Orlando as its fourth transatlantic destination from Gatwick.
The first flight to Orlando international airport took off on Saturday.
The airline is to operate a weekly service to its second destination in Florida using an expanding fleet of Boeing 787 Dreamliners.
Norwegian has seven of the new generation aircraft in service and plans to add a further ten by 2017.
It became the first low-cost carrier to offer transatlantic flights between Europe and the US in 2013 and now serves New York, Los Angeles, Fort Lauderdale and Orlando from Gatwick in addition to other US routes from Scandinavia.
Chief commercial officer Thomas Ramdahl said at the launch: “Norwegian already flies between Orlando and Oslo, and this is a very popular route both for Americans and Europeans.
“We´re therefore very happy to celebrate these new routes between London and Orlando.
“Earlier this week we also celebrated our very first flight between Copenhagen and Orlando. The travelling public deserves affordable fares and flexible tickets across the Atlantic.”