Single ship line Voyages to Antiquity is the latest to add Cuba to its list of destinations.
The cultural cruise line will sail in the Caribbean for the first time in winter 2017-18.
The company is due to confirm itineraries and expert guest speakers in the coming weeks but cruises in the region will start in November 2017.
The winter season by the line’s 350-passenger vessel Aegean Odyssey will feature a “rich programme” of ports not offered by larger cruise ships. Itineraries will go on sale next month.
The move follows extensive research to find a fitting region that can offer a huge range of places of interest throughout the winter months.
The announcement means that Voyages to Antiquity will once again offer year-round cruising.
Managing director Jos Dewing said: “Allowing our passengers to uncover the lesser-known and lesser-explored places and ports of the Caribbean and avoid those islands frequented by the larger ships and associated crowds is a really exciting development for Voyages to Antiquity.
“We know that both our agent partners and our passengers are always looking for somewhere new, and our 2017 winter season promises to uncover the culturally rich stories, history and nature of this fascinating region.”
Cuba has been featured by European lines for many years but only opened up to US companies last year led by Carnival Corporation social impact brand Fathom. Other US lines such as Royal Caribbean and Norwegian Cruise Line will a run short season of sailings to Havana this year.