Fares are being cut by up to 20% on one million Flybe seats in a week-long sale from today.
The discounts cover winter travel between October 3 and March 24, 2018.
The travel period covers the upcoming school half terms and as well as the peak holiday season over Christmas and new year.
Routes include flights departing from 17 airports including Manchester, Birmingham, Cardiff and London City, as well as the Isle of Man and the Channel Islands.
They include Manchester-Amsterdam, Birmingham-Hamburg, Liverpool-Belfast, Leeds Bradford-Newquay and Cardiff-Rome.
The seat sale includes some routes operated by Flybe franchise partners Eastern Airways, Stobart Air and Blue Islands.
Flybe is also starting a #OneInAMillion competition which will run this week by encouraging people to story about someone who is #OneInAMillion in 140 characters or less.
The regional carrier will be giving away a pair of tickets to a European destination for the seven days of the sale which runs until midnight on Wednesday.