EasyJet is adding flights to Luxembourg, Tel Aviv, Tallinn, Turin, Amsterdam, Geneva, Venice, Isle of Man and Copenhagen for winter 2012.
All are described as key city pairs which are popular with business travellers.
The expansion means more than 230,000 affordable seats have been added to the budget carrier’s winter schedule which now extends to a total of 280 routes.
All new routes will go on sale next week.
Flights to Luxembourg, Isle of Man, Tallinn and Turin will run from Gatwick with fares starting at £32.99 one-way including taxes.
The new base at Southend will gain flights to Geneva and Venice while Amsterdam will be served from Newcastle and Copenhagen from Bristol.
These are in addition to already announced services from Manchester to Tel Aviv and Birmingham to Belfast.
The Luxembourg launch sees a budget carrier on the London route for the first time.
EasyJet will initially operate four times a week from October 29 and will consider to increasing frequency at a later date.