The first Wizz Air flight to Abu Dhabi touched down on Wednesday as the airline established a new base in the Gulf state.
The Budapest-Abu Dhabi service will be followed by a route from Bucharest.
Sofia, Katowice and Cluj-Napoca flights will be added by the low-cost carrier to the UAE capital in September.
Flights from the eastern European cities will run twice a week.
Chief commercial officer George Michalopoulos said: “Wizz Air is committed to growing the airline’s network to the capital of the United Arab Emirates.
“Our new sanitising protocols will give our customers the confidence that they can safely rely on Wizz Air’s ultra-low fares to visit Abu Dhabi on board one of the world’s greenest fleet.
“Wizz Air’s ultra-low fares and route network will contribute to the further growth of Abu Dhabi’s tourism sector.”