New routes from Gatwick to New York, Los Angeles and Fort Lauderdale are being launched by budget carrier Norwegian next summer.
Five European routes are also being added together with increased frequencies on existing services.
Norwegian will use an expanding fleet of Boeing 787 Dreamliners to operate the three transatlantic services from Gatwick.
One-way flights start at an introductory rate of £149, Fort Lauderdale at £179 and Los Angeles at £199.
The airline will serve New York three times a week from July 3, Los Angeles twice a week from July 2 and Fort Lauderdale twice a week from July 4.
Santorini, Corfu, Cyprus, Sicily and Budapest are being added to the carrier’s European network from Gatwick between March and July, 2014.
Norwegian will also be introducing more frequencies to Malaga, Ibiza, Split, Dubrovnik, Majorca, Faro, Tenerife, Copenhagen and Barcelona.
The airline currently offers 320 weekly flights and 25 routes from Gatwick.
Chief executive Bjørn Kjos said: “There’s great demand for high quality flights at a low fare between the UK and the US, particularly to and from London Gatwick, where no other airline currently offers these routes.
“We are looking forward to welcoming many new customers on board our brand new aircraft. Launching long-haul routes between London Gatwick and the United States is also an important part of our strategy to expand internationally and get a stronger foothold in markets outside Scandinavia.”
Gatwick chief executive Stewart Wingate said: “This is one of the most exciting route developments since Gatwick’s change of ownership four years ago and shows the benefits to passengers of Gatwick competing with Heathrow on routes, price and service.
“Norwegian’s decision to re-establish London Gatwick’s links to strategic destinations in North America gives passengers, once again, real choice about how to get there and, importantly, provide options for affordable travel to popular business and leisure destinations.
“Norwegian’s decision to operate high quality services on new long range aircraft offering good-value fares to the US from London Gatwick is a significant industry game-changer.”