Flybe has today begun flying new routes from Aberdeen, Belfast City, Edinburgh, Exeter, Dublin and Inverness to London City.
The major expansion provides links between UK regional airports, Ireland and London.
Six Flybe aircraft were also named under the Spirit of the Regions theme at the launch event which took place at the London airport today.
Fares for the new tours start from £34.99. The Aberdeen, Belfast and Exeter routes will run up to three flights a day. There will be four flights a day between London and Edinburgh and London and Dublin, with a further two flights a day connecting London City and Inverness.
Flybe is expecting to fly over half a million passengers annually on the routes to and from London.
The airline will also start operating weekend flights from London City to Amsterdam from November 1.
Saad Hammad, chief executive of Flybe, said: “From today, purple Flybe aircraft will be a regular feature in the skies above the City of London as we begin daily services with six aircraft into/from London City Airport.
“This can only benefit our brand profile and reach over the longer term as knowledge of Flybe’s role in connecting the UK regions and Ireland with London becomes more widespread.
“Our new London City routes provide direct links for customers in the regions to the heart of London’s financial district. Flybe also offers City of London and Canary Wharf customers faster and more efficient access to the UK regions and neighbouring European destinations than travelling via Heathrow or Gatwick, or travelling by road or rail.”