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At least 13 people were killed after a coach carrying foreign students crashed on a motorway between Barcelona and Valencia.
Most of the 57 people on board were students on the Erasmus programme returning to Barcelona after a trip to a fireworks festival.
Of the 43 people injured, 28 were taken to hospital.
The accident occurred at a known accident blackspot near Freginals, 93 miles south of Barcelona. All of those who died were female, officials say.
Those on board included students from the UK, Hungary, Germany, Sweden, Norway, Switzerland, the Czech Republic, New Zealand, Italy, Peru, Bulgaria, Poland, Ireland, the Palestinian territories, Japan and Ukraine, the BBC reported.