African carrier RwandAir is to start direct flights between Heathrow and Kigali next month from.
The airline has been operating flights to London via Brussels for the past five years.
But a new non-stop service will be introduced from November 6 to cater to increased customer demand.
The direct flights go on sale from today with fares starting at £661 return.
Flights will run four times a week, an increase from the current indirect service three times a week.
The schedule also allows for connections via Kigali to 28 destinations across Africa, the Middle East and Asia.
The airline will reply two-class Airbus A330 aircraft on the route.
Chief executive Yvonne Makolo said: “We are excited to be launching direct flights to London, which are on sale from today, due to the popularity of our current services.
“The UK is an incredibly important market for us, and we know our customers will value the shorter flight times and increased connections that will be offered by the new service.”
The airline has flown between London and Kigali since May 2017 via Brussels, having initially launched flights from Gatwick.
Flights were switched to Heathrow in 2020 to improve connections.