Ryanair is to start flying from Cardiff with a winter route to Tenerife.
The Welsh airport becomes the 15th in the UK used by the budget carrier.
Weekly flights start on October 30, with promotional fares starting at £39.99 for travel in November if booked by midnight on Monday (May 19). Tickets go on sale tomorrow.
The airline hopes to carry 15,000 passengers a year on the service.
Cardiff airport chief executive Jon Horne said: “We are delighted that Ryanair has chosen Cardiff as its 15th UK departure airport and see this as a major opportunity to increase choice for our customers.
“This development fits perfectly with our strategy to grow the number of low-cost airlines and flights available from Cardiff.
“It’s great to add another major airline like Ryanair to our list and I’m sure this service will be a great success.”
Welsh government economy, science and transport minister Edwina Hart said: “This announcement is excellent news for Cardiff airport, and clearly demonstrates potential for building the offer of low-cost airlines.
“Ryanair is a major player in this sector so for them to introduce a route at Cardiff will help to build the profile of the airport and attract new customers.
“It is also excellent news for travellers who will now have more choice and flexibility. Hopefully this will be the springboard for many more Ryanair flights from Cardiff.
“This is one of several new flights operating from Cardiff since the Welsh government bought the airport and is proof that the airport is a highly attractive proposition for airlines.”