Passengers flying transatlantic from Edinburgh will be able to clear US customs before boarding their aircraft.
The Scottish airport is one of ten around the world where the US Customs and Border Protection is extending customs pre-clearance.
Others include Reykjavik in Iceland, an increasing hub for low-cost flights between Europe and the US.
The US Travel Association described the move as a “welcome development for our entry system”.
Heathrow and Manchester airports are on a list of “prioritised locations” being considered for US pre-clearance although no timeframe has been given.
US Travel Association president and chief executive Roger Dow said: “Pre-clearing passengers at foreign airports before they even board a plane to the US is great for both national security and our economy.
“Airports participating in pre-clearance must uphold rigorous security standards, which ensures that pre-cleared passengers are thoroughly vetted prior to their arrival.
“Pre-clearance also helps reduce the workload for US customs agents at domestic ports of entry, allowing them to focus on lesser-known travellers.”
He added: “Giving travelers an innovative, convenient and efficient entry process with pre-clearance sends the message that they are welcome here – and those who feel welcomed are more likely to visit again.
“From both an economic and diplomatic standpoint, modernising the customs and entry process for legitimate international visitors helps the US remain globally competitive as an attractive, welcoming destination.
“We hope to hear many more announcements like today’s in the future.”