A-Rosa plans to resume cruising on European rivers in June.
The move follows the success in both the ongoing vaccination roll-out and the measures put in place to control the pandemic across Europe.
Cruises on the Douro, Rhine and Danube rivers will restart by the middle of next month and in France by the end of June.
International passengers will be welcomed on board in line with each country’s entry and exit requirements.
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Portugal has already opened its borders to tourists while Austria will allow river cruises on the Danube again from May 19.
Slovakia and Hungary have not given dates for when hotels, including river cruises, will open but both countries are now recording low case numbers.
German federal states along the Rhine have included tourist accommodation, including river cruises, in its current reopening of tourism plans, expected to be in place by mid-June.
The Netherlands and Belgium are also expected to follow suit and in Switzerland, hotels are already open.
A four-stage plan in France is set to allow cruise and passenger ships to operate from June 30.
A-Rosa sailed for five months last year under a series of strict health and hygiene protocols.
Managing director Jorg Eichler said: “It is really encouraging that tourism in Europe finally looks like it can return soon.
“We are busy adapting and updating our current protocols in line with the latest regulations in the countries we sail through, and will announce them in the coming days.
“Our successful five months of sailing in 2020 clearly shows that cruising with A-Rosa can be safe and enjoyable.”
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